Mucosa-Associated Lymphoid Tissue Lymphoma of the Labial Minor Salivary Glands: Case Report
이정은, 한다울, 김현실, 이채나, 박연정, 권정승,
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이정은 ( Lee Jung-Eun ) -
한다울 ( Han Da-Wool ) -
김현실 ( Kim Hyun-Sil ) -
이채나 ( Lee Che-Na ) -
박연정 ( Park Youn-Jung ) -
권정승 ( Kwon Jeong-Seung ) -
Abstract
A 74-year-old female presented with a complaint of dry mouth, continuous spontaneous burning sensation in the tongue, and asymptomatic submucosal soft tissue mass on both sides of the lower labial mucosa. She refused to undergo total excision of the mass due to concern about the possibility of complications such as nerve damage because of the large size of the mass. As her clinical features and magnetic resonance imaging indicated the possibility of Sjogren’s syndrome, a biopsy of the minor salivary gland of the right lower lip was performed. Consequently, she was diagnosed with mucosa-associated lymphoid tissue (MALT) lymphoma. Although the patient had typical signs and symptoms of Sjogren’s syndrome, the histopathological result of MALT lymphoma made it impossible to determine whether the patient had a history of Sjogren’s syndrome. For patients with risk factors for MALT lymphoma, such as Sjogren’s syndrome, a biopsy of the labial minor salivary gland with immunohistochemical staining can be helpful in the diagnosis of not only Sjogren’s syndrome but also MALT lymphoma.
키워드
B-cell; Immunohistochemistry; Lymphoma; Marginal zone; Salivary gland diseases; Sjogren’s syndrome
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